In 2012, she appeared in the films Fun Size and Nobody Walks. In 2013, Levy starred in the 2013 remake of the 1981 film The Evil Dead directed by Fede Álvarez. In 2016, she collaborated with Alvarez again with her starring role in the horror film Don't Breathe. These roles have earned her scream queen status. Since 2018, Levy stars as Diane "Jackie" Torrance in the Hulu horror series Castle Rock.