She made her acting debut with the 2005 Telugu film Super, which garnered her a Filmfare Best Supporting Actress – Telugu nomination. The following year, she starred in S. S. Rajamouli's Vikramarkudu, which went to become a major commercial success. Her further releases Lakshyam (2007) and Souryam (2008), and Chintakayala Ravi (2008) were also box office successes. In 2009, Shetty played dual roles in the dark fantasy Arundhati, which garnered her critical acclaim and several awards, including her first Filmfare Award for Best Actress – Telugu, Nandi Award, Cinemaa Award for Best Actress. The following year, Shetty's portrayal of a prostitute in the acclaimed drama Vedam won her a second consecutive Best Actress Award from Filmfare and CineMaa Award. Following the success of a series of films, she established herself as one of the leading actresses of Telugu cinema.