The narrator offers a story to explain why a "draught of cool air" is the most detestable thing to him. His tale begins in the spring of 1923, when he was looking for housing in New York City. He finally settles in a converted brownstone on West Fourteenth Street. Investigating a chemical leak from the floor above, he discovers that the inhabitant directly overhead is a strange, old, and reclusive physician. One day the narrator suffers a heart attack, and remembering that a doctor lives overhead, he climbs the stairs and meets Dr. Muñoz for the first time.